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Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale.

Chemical examination of the MeOH extract of the root of Taraxacum officinale, which exhibited inhibitory activity on the formation of leukotriene B4 from activated human neutrophils, has resulted in the isolation of 14-O-beta-D-glucosyl-11,13-dihydro-taraxinic acid (1) and 14-O-beta-D-glucosyl-taraxinic acid (2). The absolute stereostructure of 1 has been established by X-ray chrystallographic examination.[1]

References

  1. Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale. Kashiwada, Y., Takanaka, K., Tsukada, H., Miwa, Y., Taga, T., Tanaka, S., Ikeshiro, Y. Journal of Asian natural products research. (2001) [Pubmed]
 
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