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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Genomic organization of the human NFAT5 gene: exon-intron structure of the 14-kb transcript and CpG-island analysis of the promoter region.

NFAT5, also known as tonicity enhancer binding protein (TonEBP) or NFATL1, is a new member of the immunologically important NFAT protein family. Despite its obvious relationship to this transcription factor family, NFAT5 shows distinct ways of regulation and function. The complete coding sequence and its alternative splice forms have been described previously. This sequence only refers to less than half of the total mRNA length. High conservation of this gene was shown among man, mouse, and pig. Here we report the cloning of the complete 14-kb cDNA sequence, its genomic organization, and a possible fourth isoform of the corresponding protein. Additionally, we describe the promoter region by CpG-island methylation analysis.[1]

References

  1. Genomic organization of the human NFAT5 gene: exon-intron structure of the 14-kb transcript and CpG-island analysis of the promoter region. Dalski, A., Schwinger, E., Zühlke, C. Cytogenet. Cell Genet. (2001) [Pubmed]
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