The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound

Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

[search][options]

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Evers, S. et al.

Evers, Hengst, Pecuch,

The impact of repetitive transcranial magnetic stimulation on pituitary hormone levels and cortisol in healthy subjects.

BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) is a new therapeutic tool in the treatment of affective disorders but only few studies on its safety exist. We aimed to determine the impact of rTMS on (neuro)endocrinological serum levels by a placebo-controlled cross-over study. METHODS: 23 healthy subjects were stimulated by rTMS in a typical paradigm used in the treatment of depression (coil placed over left dorsolateral prefrontal cortex, 10 and 20 Hz stimulation). Placebo, infrathreshold, and suprathreshold stimulation were applied in random order. The serum levels of cortisol, prolactin, FSH, and TSH were measured before and after stimulation. RESULTS: After infrathreshold stimulation, cortisol and TSH serum levels decreased mildly but significantly. All other stimulations had no significant impact on hormone levels. In female, but not in male, subjects placebo stimulation yielded a significant increase of prolactin. CONCLUSIONS: rTMS as applied for the treatment of depression leads to only very mild and safe changes of hormones. These changes, in particular the decrease of cortisol levels, might explain in part the efficacy of rTMS.[1]

References

The impact of repetitive transcranial magnetic stimulation on pituitary hormone levels and cortisol in healthy subjects. Evers, S., Hengst, K., Pecuch, P.W. Journal of affective disorders. (2001) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg