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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Clinical ergotism induced by ritonavir.

Ritonavir strongly inhibits cytochrome P450, thus altering the metabolism of other drugs. We report on an HIV-positive man who, on his 13th day of ritonavir therapy, developed severe ergotism after self-administration of low doses of ergotamine. Drug interactions, the degree of responsibility of the patient and the availability of over-the-counter medications must be considered when prescribing antiretroviral therapy.[1]

References

  1. Clinical ergotism induced by ritonavir. Vila, A., Mykietiuk, A., Bonvehì, P., Temporiti, E., Urueña, A., Herrera, F. Scand. J. Infect. Dis. (2001) [Pubmed]
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