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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Identification of a novel protease inhibitor gene that is highly expressed in the prostate.

A novel gene was identified 52 kb upstream of the gene encoding the protease inhibitor elafin ( PI3) on human chromosome 20q12-13. 1. The transcript of the new gene, denoted huWAP2, was characterized by rapid amplification of cDNA ends and DNA sequencing. The size is 774 bp and it gives rise to a polypeptide of 111 amino acid residues that is homologous to elafin and similar WAP-type protease inhibitors. By RT-PCR it was shown that the gene is highly expressed in prostate, skin, lung, and esophagus.[1]

References

  1. Identification of a novel protease inhibitor gene that is highly expressed in the prostate. Lundwall, A., Clauss, A. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
 
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