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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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AMOP, a protein module alternatively spliced in cancer cells.

This article describes a new extracellular domain--AMOP, for adhesion-associated domain in MUC4 and other proteins. This domain occurs in putative cell adhesion molecules and in some splice variants of MUC4. MUC4 splice variants are overexpressed in several tumours; in particular, they are highly expressed in pancreatic carcinomas but not in normal pancreas. The presence of AMOP in cell adhesion molecules could be indicative of a role for this domain in adhesion.[1]

References

  1. AMOP, a protein module alternatively spliced in cancer cells. Ciccarelli, F.D., Doerks, T., Bork, P. Trends Biochem. Sci. (2002) [Pubmed]
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