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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Non-surgical tubal occlusion.

Out of 151 women provided with chemical female sterilization with 3 insertions of 250 mg of quinacrine spaced 1 month apart, there were 7 pregnancies in 3 years. If these pregnancies were a result of failure to occlude the entrance to 1 or both fallopian tubes, birth events should decrease exponentially with time. Unexpectedly, the low failure rate has not decreased significantly over the 3-year observation period.[1]


  1. Non-surgical tubal occlusion. Guzman-serani, R., Potts, M., Wheeler, R.G. Advances in contraceptive delivery systems : CDS. (1985) [Pubmed]
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