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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Dueling activities of AIF in cell death versus survival: DNA binding and redox activity.

Apoptosis-inducing factor ( AIF) was originally discovered as a mitochondrial protein that, like cytochrome c, is released into the cytoplasm during cell death. New evidence suggests, however, that a redox-active enzymatic region of AIF may be antiapoptotic while a DNA binding region is proapoptotic.[1]

References

  1. Dueling activities of AIF in cell death versus survival: DNA binding and redox activity. Lipton, S.A., Bossy-Wetzel, E. Cell (2002) [Pubmed]
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