- The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo. Harmala, L.A., Ingulli, E.G., Curtsinger, J.M., Lucido, M.M., Schmidt, C.S., Weigel, B.J., Blazar, B.R., Mescher, M.F., Pennell, C.A. J. Immunol. (2002)