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Cella, D. et al.

Cella, Hughes, Peterman, Chang, Peshkin, Schwartz, Wenzel, Lemke, Marcus, Lerman,

A brief assessment of concerns associated with genetic testing for cancer: the Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire.

The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, alpha = .86), Uncertainty (9 items, alpha = .77), and Positive Experiences (4 items, alpha = .75). All 3 MICRA subscales differentiated participants who were BRCA1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants.[1]

References

A brief assessment of concerns associated with genetic testing for cancer: the Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire. Cella, D., Hughes, C., Peterman, A., Chang, C.H., Peshkin, B.N., Schwartz, M.D., Wenzel, L., Lemke, A., Marcus, A.C., Lerman, C. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. (2002) [Pubmed]

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