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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Ergoline congeners as potential inhibitors of prolactin release. 2.

In our attempts to elucidate the prolactin release inhibiting pharmacophore within the ergoline structure, we have prepared one indolealkylamine and several 2-aminotetralin derivatives. These congeners have been evaluated for inhibition of prolactin release in vivo. One congener, 5,8-dihydroxy-2-dimethylaminotetralin, and the drug M-7 significantly inhibited prolactin secretion.[1]

References

  1. Ergoline congeners as potential inhibitors of prolactin release. 2. Rusterholz, D.B., Barfknecht, C.F., Clemens, J.A. J. Med. Chem. (1976) [Pubmed]
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