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Belaaouaj, A.

Belaaouaj,

Neutrophil elastase-mediated killing of bacteria: lessons from targeted mutagenesis.

Engineering of mice deficient in neutrophil elastase ( NE) has allowed us to demonstrate the role of this protease in host defense against bacteria and to begin to understand its killing mechanism. Strategies to inhibit NE because of its involvement in tissue-destructive diseases should be reconsidered, while preserving its beneficial properties.[1]

References

Neutrophil elastase-mediated killing of bacteria: lessons from targeted mutagenesis. Belaaouaj, A. Microbes Infect. (2002) [Pubmed]

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