- M-LP, Mpv17-like protein, has a peroxisomal membrane targeting signal comprising a transmembrane domain and a positively charged loop and up-regulates expression of the manganese superoxide dismutase gene. Iida, R., Yasuda, T., Tsubota, E., Takatsuka, H., Masuyama, M., Matsuki, T., Kishi, K. J. Biol. Chem. (2003)