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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Microtubule associated protein ( MAP1A) mRNA was up-regulated by hypergravity in the rat inner ear.

Differential display analysis of differential mRNA expression in the rat inner ear under hypergravity identified two down- and four up-regulated genes. The up-regulation of microtubule associated protein 1A ( MAP1A) in one of these was confirmed by real-time polymerase chain reaction. Since MAP1A is believed to work as a cell stabilizer connecting the actin with microtubule, this is possibly a response to strengthen this stabilizer under hypergravity. The MAP1A gene is the first found to be affected by gravity change in the inner ear.[1]

References

  1. Microtubule associated protein (MAP1A) mRNA was up-regulated by hypergravity in the rat inner ear. Takumi, Y., Iijima, N., Suzuki, N., Oguchi, T., Ando, N., Hashimoto, M., Hara, H., Yamashita, H., Usami, S. Brain Res. Mol. Brain Res. (2002) [Pubmed]
 
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