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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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VBP-1 is necessary for morphogenesis in Caenorhabditis elegans.

VBP-1 has been isolated as a novel protein binding to the von Hippel-Lindau (VHL) tumor suppressor gene product. The fundamental function of the gene was examined in the nematode, Caenorhabditis elegans (C. elegans). The C. elegans VBP-1 gene was expressed in adults only in the gonads and was also expressed in early stage embryos. Double-stranded RNA interference (RNAi) against VBP-1 resulted in an arrest of embryogenesis at morula stages. This suggests that the VBP-1 product is necessary for morphogenesis.[1]

References

  1. VBP-1 is necessary for morphogenesis in Caenorhabditis elegans. Ichimiya, H., Hino, O., Kohara, Y., Ishii, N. Oncol. Rep. (2003) [Pubmed]
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