- Clara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic children. Sengler, C., Heinzmann, A., Jerkic, S.P., Haider, A., Sommerfeld, C., Niggemann, B., Lau, S., Forster, J., Schuster, A., Kamin, W., Bauer, C., Laing, I., LeSouef, P., Wahn, U., Deichmann, K., Nickel, R. J. Allergy Clin. Immunol. (2003)