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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Systemic and discoid lupus erythematosus in HIV-infected patients treated with highly active antiretroviral therapy.

Although HIV infection is often associated with several rheumatic diseases, the coexistence of this retroviral infection and systemic lupus erythematosus ( SLE) is extremely uncommon. Generally, HIV-related immunosuppression improves SLE symptoms, and antiretroviral therapy may lead to an autoimmune disease flare subsequent to the increase of circulating CD4+ cell number. Two HIV-infected female patients with SLE and discoid lupus erythematosus (DLE) diagnosed a few months after the highly active antiretroviral therapy initiation, are described. To our knowledge, this is the second case of DLE and the twenty-seventh case of SLE reported to date in association with HIV infection.[1]

References

  1. Systemic and discoid lupus erythematosus in HIV-infected patients treated with highly active antiretroviral therapy. Calza, L., Manfredi, R., Colangeli, V., D'Antuono, A., Passarini, B., Chiodo, F. International journal of STD & AIDS. (2003) [Pubmed]
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