Cytokinesis: a logical GAP.
Two complexes localize to the central spindle and regulate completion of cytokinesis: one, centralspindlin, contains a kinesin-like protein and a Rho-family GAP; the second contains Aurora B kinase. Aurora B kinase is known to regulate localization of centralspindlin and may regulate the activity of the RhoGAP component of centralspindlin.[1]References
- Cytokinesis: a logical GAP. Mishima, M., Glotzer, M. Curr. Biol. (2003) [Pubmed]
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