Antimicrobial activity of terpenoids from Trichodesma amplexicaule Roth.
T. amplexicaule Roth. has been investigated phytochemically for biologically active constituents from the benzene extract. This yielded a mixture of terpenoids: beta-sitosterol, alpha-amyrin, lupeol, hexacosanoic acid, ceryl alcohol and hexacosane. The sequential extracts, isolated terpenoids and reference antibiotics were screened for their possible bioactivities against selected pathogenic bacteria, Escherichia coli, Staphylococcus aureus and fungi, Aspergillus flavus and Penicillium chrysogenum etc. Out of the sequential extracts, the benzene extract was more potent against S. aureus (IZ = 10.36) and R. phaseoli (IZ = 10.69). The inhibition zones of isolated terpenoids were also recorded and the activity index was calculated and it was found that hexacosane was more active (IZ = 13.39) against E. coli and hexacosanoic acid had greater activity against A. flavus (IZ = 11.56). The present study deals with antimicrobial screening of sequential extracts and isolated terpenoids.[1]References
- Antimicrobial activity of terpenoids from Trichodesma amplexicaule Roth. Singh, B., Singh, S. Phytotherapy research : PTR. (2003) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
