Abstract
In an unusual paradox, asthmatics who are chronically treated with bronchodilating beta-agonists sometimes experience a worsening of their condition. A new study describes one possible mechanism and reveals a potential new therapeutic target in the treatment of asthma.
MeSH terms
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Adrenergic beta-Agonists / adverse effects
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Adrenergic beta-Agonists / therapeutic use*
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Animals
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Asthma / drug therapy*
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Bronchi / drug effects
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Humans
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Ligands
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Models, Biological
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Protein Binding
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Receptors, Adrenergic, beta-2 / metabolism
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Signal Transduction
Substances
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Adrenergic beta-Agonists
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Ligands
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Receptors, Adrenergic, beta-2