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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Antioxidant properties of carvedilol: inhibition of lipid peroxidation, protein oxidation and superoxide generation.

Oxidative stress has been suggested to be an etiological factor in cerebro- and cardiovascular disorders. We examined antioxidant activities of carvedilol, a beta- and alpha-adrenoreceptor blocker. Carvedilol suppressed lipid auto-oxidation and protein carbonyl formation in brain homogenate in a dose-dependent manner. Carvedilol also suppressed superoxide generation of human neutrophils. These properties of carvedilol should be suitable for treating hypertension resulting in cerebro- and cardiovascular diseases.[1]

References

  1. Antioxidant properties of carvedilol: inhibition of lipid peroxidation, protein oxidation and superoxide generation. Suzuki, Y., Tanaka, M., Sohmiya, M., Yoshida, T., Okamoto, K. Neurol. Res. (2003) [Pubmed]
 
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