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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Herpes simplex virus UL14 protein blocks apoptosis.

We report that an HSV-2 UL14 protein expressing cell line (14/HEp-2) was more resistant to apoptosis induced by osmotic shock and certain drugs than its parental cell line. Furthermore, HSV-1 UL14 protein deletion virus (UL14D) showed weaker inhibition of apoptosis compared to the rescued virus UL14R. The protein's anti-apoptotic function may derive from its heat shock protein-like properties.[1]

References

  1. Herpes simplex virus UL14 protein blocks apoptosis. Yamauchi, Y., Daikoku, T., Goshima, F., Nishiyama, Y. Microbiol. Immunol. (2003) [Pubmed]
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