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Malla, A.K. et al.

Malla, Norman, McLean, MacDonald, McIntosh, Dean-Lashley, Lynch, Scholten, Ahmed,

Determinants of quality of life in first-episode psychosis.

OBJECTIVE: To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP). METHOD: Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis. RESULTS: Patients presented with varying levels of QOL on different domains. The level of 'general satisfaction' was related to age of onset and social premorbid adjustment; 'weighted index of QOL' to social premorbid adjustment and inversely to educational premorbid adjustment; 'social relations' inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; 'psychological well-being' inversely to depression and educational premorbid adjustment; 'activities of daily living' to social premorbid adjustment and inversely to negative symptoms; and 'outlook on symptoms' to level of depression. CONCLUSION: Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.[1]

References

Determinants of quality of life in first-episode psychosis. Malla, A.K., Norman, R.M., McLean, T.S., MacDonald, C., McIntosh, E., Dean-Lashley, F., Lynch, J., Scholten, D., Ahmed, R. Acta psychiatrica Scandinavica. (2004) [Pubmed]

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