Science imitates art: the cloning of mice from olfactory sensory neurons.
The functional identity of an olfactory sensory neuron is defined by its expression of one odorant receptor from a large multigene family. The complexity of this process has led to speculation that DNA rearrangements are used to limit the expression of one receptor gene per cell. However, a recent report in Nature directly rules out irreversible DNA rearrangements as a mechanism for odorant receptor gene choice.[1]References
- Science imitates art: the cloning of mice from olfactory sensory neurons. Ngai, J. Cell (2004) [Pubmed]
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