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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Lewis acid-mediated cycloaddition of methylenecyclopropanes with aldehydes and imines: a facile access to indene, THF, and pyrrolidine skeletons via homoallylic rearrangement protocol.

Methylenecyclopropanes (MCPs) 1 can react with aldehydes and aldimines to give the corresponding indene, THF, and pyrrolidine cycloaddition products in the presence of BF(3).OEt(2) under mild reaction conditions.[1]

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