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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Analysis of the CCL3-L1 gene for association with HIV-1 susceptibility and disease progression.

CCL- L1 binds more potently to CCR5 than any other chemokine; it inhibits HIV-1 infection in vitro, and its gene occurs in variable copy numbers, some individuals failing to produce it. We analysed the frequency of the absence of CCL3-L1 in 268 Caucasian Australian HIV-1 patients and 260 uninfected individuals. A CCL- L1-negative genotype frequency of 2.3% was found in HIV-1 negative individuals. No association was found between the absence of CCL3-L1 and susceptibility to, or rate of progression of, HIV-1 infection.[1]

References

  1. Analysis of the CCL3-L1 gene for association with HIV-1 susceptibility and disease progression. Bugeja, M.J., Booth, D.R., Bennetts, B.H., Guerin, J., Kaldor, J.M., Stewart, G.J. AIDS (2004) [Pubmed]
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