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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Greene, C.M. et al.

Greene, McElvaney, O'Neill, Taggart,

Secretory leucoprotease inhibitor impairs Toll-like receptor 2- and 4-mediated responses in monocytic cells.

Secretory leucoprotease inhibitor (SLPI) is an anti-inflammatory antiprotease which can inhibit lipopolysaccharide-induced NF-kappaB activation. We examined its ability to inhibit NF-kappaB activation induced by lipoteichoic acid and investigated the effects of oxidation or complex formation with neutrophil elastase on SLPI's anti-inflammatory properties in U937 myelomonocytic cells and macrophages.[1]

References

Secretory leucoprotease inhibitor impairs Toll-like receptor 2- and 4-mediated responses in monocytic cells. Greene, C.M., McElvaney, N.G., O'Neill, S.J., Taggart, C.C. Infect. Immun. (2004) [Pubmed]

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