Abstract
The aim of this article is to highlight a novel treatment for the symptoms of chronic urethral and trigonal irritation. A patient with severe urethral hyperaesthesia who derived almost complete alleviation of symptoms with topical application of a tricyclic antidepressant cream is described. The possible modes of action of tricyclics when used via the topical route of administration are described. Topical application of a tricyclic antidepressant cream may alleviate the symptoms of urethral hyperaesthesia.
MeSH terms
-
Administration, Topical
-
Adult
-
Antidepressive Agents, Tricyclic / therapeutic use*
-
Dose-Response Relationship, Drug
-
Doxepin / therapeutic use*
-
Drug Administration Schedule
-
Follow-Up Studies
-
Humans
-
Male
-
Risk Assessment
-
Severity of Illness Index
-
Treatment Outcome
-
Urinary Bladder, Neurogenic / complications
-
Urinary Bladder, Neurogenic / diagnosis*
-
Urinary Catheterization
-
Urination Disorders / complications
-
Urination Disorders / diagnosis
-
Urination Disorders / drug therapy*
-
Urodynamics
Substances
-
Antidepressive Agents, Tricyclic
-
Doxepin