1 Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China. madw@mail.sioc.ac.cn
CuI/N,N-dimethylglycine-catalyzed coupling reaction of aryl halides with terminal alkynes is carried out in DMF at 100 degrees C to provide the corresponding coupling products in good to excellent yields with a great diversity.