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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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CD4 cell recovery during successful antiretroviral therapy in naive HIV-infected patients: the role of intravenous drug use.

We evaluated the impact of HIV risk practice on immune reconstitution in a prospective cohort of 288 patients (176 former injecting drug users) who maintained complete virus suppression for more than 24 months. Significant differences in CD4 cell counts at 6 and 24 months were detected. Multivariate analysis showed that drug use was an independent predictor of poor immunological recovery. Injection drug abuse impairs short and long-term CD4 cell recovery in HIV-positive patients initiating successful highly active antiretroviral therapy.[1]

References

  1. CD4 cell recovery during successful antiretroviral therapy in naive HIV-infected patients: the role of intravenous drug use. Dronda, F., Zamora, J., Moreno, S., Moreno, A., Casado, J.L., Muriel, A., Pérez-Elías, M.J., Antela, A., Moreno, L., Quereda, C. AIDS (2004) [Pubmed]
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