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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Investigation of anti-inflammatory and antinociceptive activities of Lantana trifolia.

The anti-inflammatory activity of Lantana trifolia (Verbenaceae) was determined by carrageenan, serotonin and histamine-induced rat paw edema and the analgesic activity of this plant was studied by acetic acid-induced writhings and tail flick tests in mice. Lantana trifolia extracts (at 30 mg/kg) inhibited carrageenan and histamine-induced rat paw edema. Although the extracts did not produce any effect on acetic acid-induced writhings, they all develop a significant increase on tail flick antinociceptive index (doses varying between 1 and 30 mg/kg), indicating a spinal antinociceptive effect. These results provide support for the use of Lantana trifolia in relieving inflammatory pain.[1]

References

  1. Investigation of anti-inflammatory and antinociceptive activities of Lantana trifolia. Silva, G.N., Martins, F.R., Matheus, M.E., Leitão, S.G., Fernandes, P.D. Journal of ethnopharmacology. (2005) [Pubmed]
 
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