miRNAs: whys and wherefores of miRNA-mediated regulation

Curr Biol. 2005 Jun 21;15(12):R458-60. doi: 10.1016/j.cub.2005.06.015.

Abstract

MiRNAs are assumed to be important in animal development and physiology, but their specific roles in vivo are still poorly understood. New bioinformatic and genetic studies are setting the stage for unraveling the specific biological functions of miRNAs.

Publication types

  • Review

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics
  • Computational Biology / methods
  • Drosophila / genetics
  • Gene Expression Regulation*
  • MicroRNAs / physiology*
  • Molecular Biology / methods
  • Mutation
  • Organ Specificity
  • Ribonuclease III / genetics
  • Transcription Factors / genetics
  • Transcription Factors / metabolism

Substances

  • MicroRNAs
  • Transcription Factors
  • Ribonuclease III