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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Synthesis of some floctafenine derivatives of expected anti-inflammatory/analgesic activity.

New derivatives related to floctafenine were synthesized and representative examples were screened for their anti-inflammatory and analgesic activities. All compounds tested were found to exhibit anti-inflammatory and analgesic activities and some were more potent than the references, floctafenine and indomethacin, in carragenan-induced rat's paw edema. None of the tested compounds showed an ulcerogenic effect on the p-benzoquinone-induced writhing test in mice.[1]

References

  1. Synthesis of some floctafenine derivatives of expected anti-inflammatory/analgesic activity. Hegazy, G.H., Taher, A., El-Zaher, A.A. Arch. Pharm. (Weinheim) (2005) [Pubmed]
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