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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Recovery of rod-mediated a-wave during light-adaptation in mGluR6-deficient mice.

The purpose of this study was to compare the a-waves of mGluR6-deficient mice (KO) to that of wild-type mice (WT), and to determine whether the light-adapted electroretinogram of the KO mice originate exclusively from cones. Dark-adapted a-waves were recorded under the same conditions from both types of mice. With a 96-cd/m(2) background, the a-wave from both types of mice showed a rapid recovery over a 50-min period. The analysis of the a-waves in KO mice indicated that the recovery was determined mainly by the rod component. The light-adapted b-wave of WT mice showed no corresponding recovery. We conclude that rod contribution must be considered in the analyses of the light-adapted a-waves of KO mice.[1]

References

  1. Recovery of rod-mediated a-wave during light-adaptation in mGluR6-deficient mice. Ueda, Y., Tammitsu, N., Imai, H., Honda, Y., Shichida, Y. Vision Res. (2006) [Pubmed]
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