Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space

Angew Chem Int Ed Engl. 2006 Feb 13;45(8):1236-41. doi: 10.1002/anie.200502746.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation*
  • Directed Molecular Evolution*
  • Enzymes / chemistry*
  • Epoxide Hydrolases / chemistry
  • Fungal Proteins / chemistry
  • Models, Molecular
  • Molecular Conformation
  • Protein Conformation
  • Random Allocation

Substances

  • Enzymes
  • Fungal Proteins
  • Epoxide Hydrolases