- Caspase-8 activation and oxidative stress are involved in the cytotoxic effect of beta-amyloid on rat brain microvascular endothelial cells. Folin, M., Baiguera, S., Fioravanzo, L., Conconi, M.T., Grandi, C., Nussdorfer, G.G., Parnigotto, P.P. Int. J. Mol. Med. (2006)