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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Preparation and characterization of monoclonal antibody against protein TREM-like transcript-1 ( TLT-1).

TREM-like transcript-1 ( TLT-1) was initially characterized as the putative inhibitory receptor within the TREM locus on chromosome 6 and was suggested to play a critical role in modulating TREM-associated immunity. Recently, TLT-1 was found not to function as an inhibiting member of the TREM family; however, it may play a significant role in maintaining vascular hemostasis, coagulation, and inflammation at sites of injury through its location in platelets. In this study, we have successfully generated a monoclonal antibody that can be applied to assays, including enzyme-linked immunosorbent assay (ELISA), Western immunoblotting, immunofluorescence, and Fluorescence-Activated Cell Sorter (Becton-Dickinson) (FACS), for the study of TLT-1 functions in physiological and pathological conditions.[1]

References

  1. Preparation and characterization of monoclonal antibody against protein TREM-like transcript-1 (TLT-1). Lu, Y.T., Yen, C.Y., Ho, H.C., Chen, C.J., Wu, M.F., Hsieh, S.L. Hybridoma (2005) (2006) [Pubmed]
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