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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response, an update.

Leptin was originally identified as an adipocyte-derived cytokine with a key role in the regulation of the energy balance. Subsequent research revealed that leptin's biological action is not restricted to its effects on appetite and food intake, but instead has a much more pleiotropic character. There is now ample evidence that leptin has important functions in reproduction, hematopoiesis, HPA-axis endocrinology and angiogenesis. In this review we have focused on the effects of leptin in the antigen-specific immunity and in the inflammatory effector system.[1]

References

  1. A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response, an update. Waelput, W., Brouckaert, P., Broekaert, D., Tavernier, J. Current medicinal chemistry. (2006) [Pubmed]
 
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