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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Mood fluctuations in people putatively at risk for bipolar disorders.

OBJECTIVES: The dysregulation of the Behavioural Activation System ( BAS) is discussed as a vulnerability marker for bipolar disorders, resulting in fluctuations of activity and mood. People putatively at risk for bipolar disorders (BD) should therefore show mood fluctuations. METHOD: Using the "Hypomanic Personality Scale" (HPS) three groups of young adults with high (N=17), medium (N=19), and low scores (N=18) were selected and completed a 28-day diary including CES-D and PANAS. RESULTS: People at risk for bipolar disorders exhibited high levels of manic symptoms, positive and negative affect. They also generally reported more mood instability. CONCLUSIONS: The results support the hypothesis that fluctuations of mood and symptoms might be a core characteristic of the hypothesized vulnerability for BD. These fluctuations of mood were, however, not restricted to positive affect as a dysregulation of the BAS would suggest.[1]

References

  1. Mood fluctuations in people putatively at risk for bipolar disorders. Hofmann, B.U., Meyer, T.D. The British journal of clinical psychology / the British Psychological Society. (2006) [Pubmed]
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