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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Lignans from Saussurea conica and their NO production suppressing activity.

Three new lignan derivatives, conicaols A and B and conicaoside, together with seven known compounds were identified from Saussurea conica. Their structures were elucidated by spectral methods including 1D and 2D NMR techniques. Six 2,3-dibenzylbutyrolactone-type lignans were biologically evaluated, and two of them, arctigenin and matairesinol, showed potent activity to suppress NO production in vitro in LPS-activated macrophages of SD rat.[1]

References

  1. Lignans from Saussurea conica and their NO production suppressing activity. Fan, C.Q., Zhu, X.Z., Zhan, Z.J., Ji, X.Q., Li, H., Yue, J.M. Planta Med. (2006) [Pubmed]
 
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