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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Biodegradation of 8-anilino-1-naphthalenesulfonic acid by Pseudomonas aeruginosa.

Pseudomonas aeruginosa, isolated from soil near tannery effluent was able to degrade 8-anilino-1-naphthalenesulfonic acid (ANSA), a sulfonated aromatic amine. The organism degraded this amine up to a concentration of 1,200 mg l(-1) using glucose and ammonium nitrate as carbon and nitrogen sources respectively. The degradation started when the organism reached its late exponential growth phase. Salicylic acid and beta-ketoadipic acid were identified as intermediate compounds using HPLC and GC-MS and provide evidence for ortho pathway reactions. Further proof for the pathway is obtained from the dioxygenase activity of the strain growing exponentially in medium with ANSA and glucose.[1]


  1. Biodegradation of 8-anilino-1-naphthalenesulfonic acid by Pseudomonas aeruginosa. Valli Nachiyar, C., Suseela Rajakumar, G. J. Ind. Microbiol. Biotechnol. (2006) [Pubmed]
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