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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.

The authors conducted a double-blind, placebo-controlled, crossover study to investigate the efficacy of oral zolmitriptan in the treatment of migraine in children and adolescents. Patients (n = 32) received placebo, zolmitriptan 2.5 mg, and ibuprofen 200 to 400 mg to treat three consecutive migraine attacks. Pain relief rates after 2 hours were 28% for placebo, 62% for zolmitriptan, and 69% for ibuprofen (p < 0.05). Both drugs are well tolerated with only mild side effects.[1]

References

  1. Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen. Evers, S., Rahmann, A., Kraemer, C., Kurlemann, G., Debus, O., Husstedt, I.W., Frese, A. Neurology (2006) [Pubmed]
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