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Reassignment of the configuration of salvianolic acid B and establishment of its identity with lithospermic acid B.

Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures except for the configurational assignments of two stereocenters. Through chemical correlation between a degradation product of salvianolic acid B and synthetic material, the absolute configuration of salvianolic acid B has been corrected to establish that salvianolic acid B and lithospermic acid B are in fact the same compound.[1]

References

  1. Reassignment of the configuration of salvianolic acid B and establishment of its identity with lithospermic acid B. Watzke, A., O'Malley, S.J., Bergman, R.G., Ellman, J.A. J. Nat. Prod. (2006) [Pubmed]
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