- Lack of Association of the 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Gene 83,557insA and Hexose-6-Phosphate Dehydrogenase Gene R453Q Polymorphisms with Body Composition, Adrenal Androgen Production, Blood Pressure, Glucose Metabolism, and Dementia. Smit, P., Dekker, M.J., de Jong, F.J., van den Beld, A.W., Koper, J.W., Pols, H.A., Brinkmann, A.O., de Jong, F.H., Breteler, M.M., Lamberts, S.W. J. Clin. Endocrinol. Metab. (2007)