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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Expression of phosphorylcholine by Histophilus somni induces bovine platelet aggregation.

Histophilus somni-induced platelet aggregation was inhibited by antagonists of the platelet-activating factor (PAF) receptor but not inhibitors of PAF synthesis. In addition, H. somni cells expressing phosphorylcholine (ChoP) induced aggregation, while ChoP(-) H. somni cells did not. This suggests that H. somni ChoP may induce platelet aggregation via interactions with the PAF receptor.[1]

References

  1. Expression of phosphorylcholine by Histophilus somni induces bovine platelet aggregation. Kuckleburg, C.J., Elswaifi, S.F., Inzana, T.J., Czuprynski, C.J. Infect. Immun. (2007) [Pubmed]
 
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