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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Novel Synthetic Approach Toward (+/-)-beta-Cuparenone via Palladium-Catalyzed Tandem Heck Cyclization of 1-Bromo-5-methyl-1-aryl-hexa-1,5-dien-3-ol Derivatives.

A novel and convenient synthetic route toward (+/-)-beta-cuparenone and many other sesquiterpene natural product precursors has been developed via palladium-catalyzed tandem Heck cyclization of 1-bromo-5-methyl-1-aryl-hexa-1,5-dien-3-ols.[1]

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