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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Antegrade and retrograde endoscopic approach in the establishment of a neo-esophagus: a novel technique.

BACKGROUND: Although total obstruction or secondary atresia of the esophagus is extremely rare, high-grade strictures are not uncommon. The retrograde approach was previously described to achieve dilation when the conventional antegrade method fails. SETTING: Gastroenterology laboratory in a tertiary referral center. PATIENT: A 30-year-old man with congenital T-cell immunodeficiency had complete esophageal obstruction after a severe episode of cryptococcal meningitis that required prolonged nasogastric intubation. For the next 3 years, he had daily episodes of regurgitations and several hospitalizations for aspiration pneumonia. A barium study revealed a dilated megaesophagus, with no contrast reaching to the stomach. INTERVENTION: Initially, a new track was created by using access from above and below the obstruction. This was followed by placement of a self-expandable silicone stent after allowing sufficient time for the new track to mature. MAIN OUTCOME MEASUREMENTS: Restoration of esophageal continuity, which allowed resolution of the patient's aspiration pneumonia and resumption of oral feeding. CONCLUSIONS: Complete esophageal obstruction after prolonged nasogastric intubation is a rare but serious complication. A novel endoscopic approach can be used to restore esophageal continuity, minimize complications, and avoid major reconstructive surgeries.[1]

References

  1. Antegrade and retrograde endoscopic approach in the establishment of a neo-esophagus: a novel technique. Al-Haddad, M., Pungpapong, S., Wallace, M.B., Raimondo, M., Woodward, T.A. Gastrointest. Endosc. (2007) [Pubmed]
 
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