Regulating the social brain: a new role for CD38

Neuron. 2007 May 3;54(3):353-6. doi: 10.1016/j.neuron.2007.04.011.

Abstract

Centrally released oxytocin regulates maternal behavior, social memory, and social bonding. A recent paper by Jin et al. published in Nature demonstrates that the transmembrane receptor CD38 plays a critical role in regulating social behaviors by regulating the release of OT from hypothalamic neurons.

MeSH terms

  • ADP-ribosyl Cyclase 1 / physiology*
  • Animals
  • Hypothalamus / cytology*
  • Mice
  • Models, Biological
  • Neurons / metabolism*
  • Oxytocin / metabolism
  • Social Behavior*

Substances

  • Oxytocin
  • ADP-ribosyl Cyclase 1