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Kato, N. et al.

Molecular structure of the Japanese hepatitis C viral genome.

The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528) indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase, NTPase and RNA-dependent RNA polymerase.[1]

References

Molecular structure of the Japanese hepatitis C viral genome. Kato, N., Hijikata, M., Nakagawa, M., Ootsuyama, Y., Muraiso, K., Ohkoshi, S., Shimotohno, K. FEBS Lett. (1991) [Pubmed]

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