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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Hepatic fibrin-ring granulomas: a clinicopathologic study of 23 patients.

Twenty-three patients with characteristic hepatic fibrin-ring granulomas were studied. Q fever accounted for 10 cases (43%), visceral leishmaniasis for five cases (22%), boutonneuse fever for two cases (9%), and toxoplasmosis, Hodgkin's disease, and allopurinol hypersensitivity for one case each (4%). The etiology remained undetermined in three cases (13%). This report broadens the range of etiologies of hepatic fibrin-ring granulomas to include boutonneuse fever and toxoplasmosis in the differential diagnosis of ring granulomas, and it could serve as a guideline to the clinician and pathologist for the most frequent categories of disease associated with this morphologic pattern.[1]

References

  1. Hepatic fibrin-ring granulomas: a clinicopathologic study of 23 patients. Marazuela, M., Moreno, A., Yebra, M., Cerezo, E., Gómez-Gesto, C., Vargas, J.A. Hum. Pathol. (1991) [Pubmed]
 
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